Prevailing vitamin D status influences mitochondrial and glycolytic bioenergetics in peripheral blood mononuclear cells obtained from adults
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- 作者：Emily K. Caltona ; Kevin N. Keaneb ; Mario J. Soaresa ; m.soares@curtin.edu.au" class="auth_mail" title="E-mail the corresponding author ; Jordan Rowlandsb ; Philip Newsholmeb ; philip.newsholme@curtin.edu.au" class="auth_mail" title="E-mail the corresponding author
- 关键词：2DG ; 2-deoxyglucose ; BHI ; bioenergetic health index ; FM ; fat mass ; FFM ; fat free mass ; PBMCs ; peripheral blood mononuclear cells ; PPR ; proton production rate ; OCR ; oxygen consumption rate ; RQ ; respiratory quotient ; RMR ; resting metabolic rate ; UCP ; uncoupling proteins ; VDR ; vitamin D receptor
- 刊名：Redox Biology
- 出版年：2016
- 出版时间：December 2016
- 年：2016
- 卷：10
- 期：Complete
- 页码：243-250
- 全文大小：433 K
文摘
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A model linking vitamin D status and the bioenergetic profile of PBMCs is proposed.
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Adults with <50 nmol/L had greater oxidative and glycolytic metabolism.
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Bioenergetic Health Index was positively related to fasting insulin sensitivity.