Steroid receptor RNA activator: Biologic function and role in disease
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- 作者：Chan Liua ; b ; 1 ; Hong-Tao Wuc ; 1 ; Neng Zhud ; Ya-Ning Shia ; Zheng Liua ; b ; Bao-Xue Aoa ; b ; Duan-Fang Liaoa ; Xi-Long Zhenga ; e ; Li Qina ; lqin1011@126.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：AF-2 ; activation function-2 ; AR ; androgen receptor ; C/EBPα ; ccaat-enhancer-binding protein α ; CTCF ; CCCTC-binding factor ; Ddx5 ; DEAD box protein 5 ; ERα ; estrogen receptor α ; GR ; glucocorticoid receptor ; Hes1 ; hairy and enhancer of split-1 ; HP1γ ; heterochromatin protein 1γ ; JNK ; c-Jun N-terminal kinases ; lncRNA ; long noncoding RNA ; MyoD ; myogenic differentiation 1 ; NANOG ; homeobox protein NANOG ; NR ; nuclear receptor(s) ; p38 MAPK ; mitogen-activated protein kinase ; PACT ; protein kinase RNA activato
- 刊名：Clinica Chimica Acta
- 出版年：2016
- 出版时间：1 August 2016
- 年：2016
- 卷：459
- 期：Complete
- 页码：137-146
- 全文大小：982 K
文摘
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SRA expression may serve as a new prognostic marker in breast cancer patients.
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Targeting SRA is a promising therapeutic strategy for breast cancer.
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SRA is post-transcriptionally modified, which modulate its activities.