刊名:Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics
出版年:2017
出版时间:January 2017
年:2017
卷:1865
期:1
页码:76-87
全文大小:1668 K
卷排序:1865
文摘
RNase A deamidation affects its oligomerization occurring via 3D domain swapping. IsoAsp derivatives lower oligomerization more than the corresponding Asp products. Extensive deamidation almost nullifies RNase A self-association tendency. It's the first report associating protein deamidation to zero aggregation tendency.