Significance of metabolite extraction method for evaluating sulfamethazine toxicity in adult zebrafish using metabolomics
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- 作者：Ryan De Sottoa ; Carl Medrianob ; Yunchul Choc ; Kwang-Seol Seokd ; Youngja Parkb ; yjhwang@korea.ac.kr" class="auth_mail" title="E-mail the corresponding author ; Sungpyo Kima ; ub1905ub@korea.ac.kr" class="auth_mail" title="E-mail the corresponding author
- 关键词：Environmental metabolomics ; Danio rerio ; Antibiotics
- 刊名：Ecotoxicology and Environmental Safety
- 出版年：2016
- 出版时间：May 2016
- 年：2016
- 卷：127
- 期：Complete
- 页码：127-134
- 全文大小：2729 K
文摘
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Bligh and Dyer method showed more signals in 1H NMR Spectroscopy than SPE method.
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aPLCMS data from Q-TOF LC/MS aligned more features in Bligh and Dyer method.
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There were 90 and 37 metabolic pathway hits for Bligh and Dyer and SPE respectively.
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Bligh and Dyer is a good extraction method for environmental metabolomics samples.