Dietary phytic acid prevents fatty liver by reducing expression of hepatic lipogenic enzymes and modulates gut microflora in rats fed a high-sucrose diet
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- 作者：Ayaka Sekita ; M.S.a ; Yukako Okazaki ; Ph.D.a ; yokazaki@fujijoshi.ac.jp" class="auth_mail" title="E-mail the corresponding author ; Tetsuyuki Katayama ; Ph.D.b
- 关键词：Phytic acid ; High-sucrose diet ; Fatty liver ; Glucose-6-phosphate dehydrogenase ; Malic enzyme 1 ; Fatty acid synthetase ; Gut microflora
- 刊名：Nutrition
- 出版年：2016
- 出版时间：June 2016
- 年：2016
- 卷：32
- 期：6
- 页码：720-722
- 全文大小：186 K
文摘
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We examined the effect of dietary phytate on fatty liver and gut microflora in rats.
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Phytate prevents fatty liver and modulates gut microflora in rats fed a high-sucrose diet.
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Dietary phytate downregulates the gene expression of hepatic lipogenic enzymes.
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Phytate increases Lactobacillus spp. and decreases Clostridium spp. in rat feces.
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We report the relations among phytate intake, fatty liver, and gut microflora in rats.