Interictal epileptiform discharge effects on neuropsychological assessment and epilepsy surgical planning
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- 作者：Daniel L. Dranea ; b ; c ; ddrane@emory.edu" class="auth_mail" title="E-mail the corresponding author ; Jeffrey G. Ojemannd ; Michelle S. Kimc ; Robert E. Grosse ; John W. Millerc ; d ; R. Edward Faught Jr.a ; David W. Loringa ; b
- 关键词：Interictal epileptiform discharges ; Surgical outcome ; Neuropsychological assessment
- 刊名：Epilepsy & Behavior
- 出版年：2016
- 出版时间：March 2016
- 年：2016
- 卷：56
- 期：Complete
- 页码：131-138
- 全文大小：317 K
文摘
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We review extensive animal and human research suggesting interictal epileptiform discharges (IEDs) may affect cognition.
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Case series data demonstrate cognitive dysfunction is associated with IEDs using simultaneous EEG during testing.
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The occurrence of IEDs can lead to spurious conclusions about neurocognitive data.
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Not appreciating IED effects can misinform epilepsy surgical planning and risk prediction, and obscure outcome research.
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Understanding IED effects on cognition can improve seizure onset classification and illuminate brain-behavior relationships.