Alteration of amiloride-sensitive salt taste nerve responses in aldosterone/NaCl-induced hypertensive rats
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- 作者：Takashi Sakamotoa ; Akihiko Fujiib ; Naoko Saitoa ; Hidehiko Kondoa ; Atsushi Ohuchia ; oouchi.atsushi@kao.co.jp" class="auth_mail" title="E-mail the corresponding author
- 关键词：ENaC ; epithelial sodium channel ; RAAS ; renin&ndash ; angiotensin&ndash ; aldosterone system ; Aldo ; aldosterone ; Angiotensin II ; Ang II ; TRCs ; taste receptor cells ; CT ; chorda tympani ; SBP ; systolic blood pressure.
- 刊名：Neuroscience Research
- 出版年：2016
- 出版时间：July 2016
- 年：2016
- 卷：108
- 期：Complete
- 页码：60-66
- 全文大小：640 K
文摘
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We studied the mechanism of changes of salt taste sensitivity in hypertensive rats.
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Daily sodium intake was high in hypertensive rats.
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Amiloride-sensitive salt taste nerve responses were low in hypertensive rats.
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Gene expression of αENaC in taste papillae was low in hypertensive rats.