- 作者：Cihangir Mutlu ; Ercan ; Nam?k Kemal ; Duru ; Kazim Emre ; Karasahin ; Hakan ; Coksuer ; ; ; coksuer@gmail.com ; Murat ; Dede ; Iskender ; Baser
- 关键词：Endometrioma ; Laparoscopic stripping surgery ; AFC ; Ovarian Doppler ; AMH
- 刊名：European Journal of Obstetrics and Gynecology and Reproductive Biology
- 出版年：2011
- 出版时间：October 2011
- 年：2011
- 卷：158
- 期：2
- 页码：280-284
- 全文大小：215 K
Objective
To evaluate the ovarian reserve after laparoscopic stripping of unilateral endometriomas by comparing the operated and non-operated ovaries.Study design
Bilateral ovarian volumes, antral follicle counts, and stromal blood flows were assessed by ultrasonography and anti-mullerian hormone (AMH) levels were analysed in 36 patients who had undergone laparoscopic cystectomy for unilateral ovarian endometrioma.
Results
Mean antral follicle counts (AFC) of the operated side ovaries were significantly lower on the second postoperative day (3.1 ¡À 2.4 vs 5.2 ¡À 3.7; mlns="""">p < 0.05) and in the third month (3.7 ¡À 2.1 vs 6.4 ¡À 2.7; mlns="""">p < 0.05). Pulsatility indices of the operated ovaries were significantly decreased on the second postoperative day (2.22 ¡À 0.46 vs 1.76 ¡À 0.51; mlns="""">p < 0.05) while resistance indices were increased (0.81 ¡À 0.06 vs 0.88 ¡À 0.13; mlns="""">p < 0.05). Doppler parameters had recovered and a non-significant decrease in AMH levels of the patients was recorded in the third month after surgery (2.03 ¡À 0.41 ng/mL vs 1.95 ¡À 0.62 ng/mL; mlns="""">p > 0.05).
Conclusion
Although laparoscopic stripping of endometriomas seems to affect the ovarian reserve in terms of AFCs, it does not have a significant negative impact at the end of three months as assessed by ovarian volumes, Doppler indices and AMH levels. Endometrioma surgery techniques are important in preserving normal functioning ovaries and further studies are necessary for optimising these surgical approaches.