Preparation and characterization of aligned porous PCL/zein scaffolds as drug delivery systems via improved unidirectional freeze-drying method
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- 作者：Zeinab Fereshteha ; b ; c ; z.fereshteh89@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Mohammadhossein Fathic ; d ; Akbar Bagrie ; f ; Aldo R. Boccaccinia
- 关键词：Freeze-drying ; Aligned PCL/zein scaffolds ; Protein release ; Drug delivery ; Controlled release
- 刊名：Materials Science & Engineering C
- 出版年：2016
- 出版时间：1 November 2016
- 年：2016
- 卷：68
- 期：Complete
- 页码：613-622
- 全文大小：2747 K
文摘
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We synthesized an aligned porous PCL/zein scaffolds by improved unidirectional freeze-drying.
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Our results signify an acceptable way for controlling in vitro degradation behavior of the polymeric composite scaffold.
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The PCL/zein scaffolds are proposed as a suitable candidate in tissue engineering strategies for bone defect.