Alternative splicing of SMPD1 coding for acid sphingomyelinase in major depression

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• 作者：Cosima Rhein^a ; ^b ; ^{Cosima.Rhein@uk-erlangen.de} ; Martin Reichel^a ; ¹ ; Marcel Kramer^c ; ^d ; Andrea Rotter^a ; Bernd Lenz^a ; Christiane Mü ; hle^a ; Erich Gulbins^e ; Johannes Kornhuber^a
• 关键词：Acid sphingomyelinase ; Alternative splicing ; Major depression ; Functional inhibitors of ASM activity (FIASMAs) ; Antidepressant drugs ; Fluoxetine ; Paroxetine
• 刊名：Journal of Affective Disorders
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：209
• 期：Complete
• 页码：10-15
• 全文大小：215 K
• 卷排序：209

文摘

ASM alternative splicing occurs less frequently in MDD patients compared to control Functional inhibitors of ASM activity decrease ASM alternative splicing frequency ASM alternative splicing frequency as a potential novel biomarker for MDD