The evolution of ERMIONE in mitochondrial biogenesis and lipid homeostasis: An evolutionary view from comparative cell biology
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- 作者：Jeremy G. Widemana ; jeremy.grant.wideman@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Sergio A. Muñ ; oz-Gó ; mezb
- 关键词：ERMES ; ERMIONE ; MICOS ; MCS ; Membrane contact sites ; Evolutionary cell biology
- 刊名：Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids
- 出版年：2016
- 出版时间：August 2016
- 年：2016
- 卷：1861
- 期：8
- 页码：900-912
- 全文大小：1225 K
文摘
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ERMIONE is a network of interacting proteins in control of mitochondrial biogenesis.
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ERMIONE has a core formed by ERMES-MICOS-SAM-TOM and a shell of accessory proteins.
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ERMIONE localizes mitochondrial biogenic processes at MCSs.
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ERMIONE evolution reflects the integration of mitochondria with their hosts.
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ERMIONE has bacterial roots; it has both simplified and complexified in eukaryotes.