H1:IC31 vaccination is safe and induces long-lived TNF-α+IL-2+CD4 T cell responses in M. tuberculosis infected and uninfected adolescents: A randomized trial
H1:IC31 vaccination was well tolerated and had an acceptable safety profile. Two vaccinations of 15 μg H1:IC31 induced the most durable immune response. H1:IC31 induced long-lived memory CD4 T cells that co-express TNFα and IL-2.