Activity/remission of systemic lupus erythematosus: Lymphocyte phenotypic alterations in relation to each

详细信息    查看全文

• 作者：Hern&aacute ; ndez ; M.P. ; Reyes ; E. ; Monserrat ; J. ; Martí ; nez-Martin ; B. ; Villa ; L. ; Esquivel ; F. ; et. al.
• 刊名：Immunology Letters
• 出版年：1997
• 出版时间：May, 1997
• 年：1997
• 卷：56
• 期：1-3
• 页码：318
• 全文大小：158 K

文摘

Introduction: Systemic Lupus Erythematosus (SLE) is an autoimmune disease whose clinical manifestations are characterised by periods of exacerbation interspersed with periods of relative quiescence. Autoantibody overproduction is a hallmark of the disease which has been ascribed to a B-cell hyperactivity; which of late its thought to be T-cell driven and/or sustained. Thus we have studied phenotypic alterations found in CD2+ (T and NK) cells from SLE patients in relation to the activity of the disease.