Trends in lower extremity amputations in people with and without diabetes in England, 1996–2005

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• 作者：Eszter Panna Vamos ; Alex Bottle ; Azeem Majeed ; Christopher Millett
• 关键词：Hospital admissions ; Lower extremity amputation ; Diabetes
• 刊名：Diabetes Research and Clinical Practice
• 出版年：2010
• 出版时间：February 2010
• 年：2010
• 卷：87
• 期：2
• 页码：275-282
• 全文大小：487 K

文摘

Aims

To examine trends in non-traumatic lower extremity amputations over a 10-year-period in people with and without diabetes (DM) in England.

Methods

All individuals admitted to NHS hospitals for non-traumatic amputations between 1996 and 2005 in England were identified using hospital activity data. Postoperative and 1-year mortality were examined between 2000 and 2004.

Results

There was a reduction in minor and major amputations during the study period. The number of type 1 DM- and non-DM-related minor amputations decreased by 11.4 % and 32.4 % , respectively, while the number of type 2 DM-related minor amputations almost doubled. The incidence of type 1- and non-DM-related minor amputations decreased from 1.5 to 1.2 and from 8.1 to 5.1/100,000 population, respectively, while type 2 DM-related amputations increased from 2.4 to 4.1/100,000 population. The number of type 1- and non-DM-related major amputations declined by 41 % and 22 % , respectively, whereas type 2 DM-related amputations increased by 43 % . The incidence of type 2 DM-related amputations increased from 2.0 to 2.7/100,000 population. Overall perioperative and 1-year mortality did not significantly change between 2000 and 2004.

Conclusions

While several factors may explain the increase in type 2 DM-related LEAs, these findings highlight the importance of diabetes prevention strategies and controlling risk factors for LEAs in people with diabetes.