Biomechanical assessment in models of glaucomatous optic neuropathy
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- 作者：Thao D. Nguyena ; C. Ross Ethierb ; c ; d ; e ; ross.ethier@bme.gatech.edu" class="auth_mail" title="E-mail the corresponding author
- 关键词：Glaucoma ; Biomechanics ; Mechanobiology ; Optic nerve head ; Deformation ; Measurement ; Computation
- 刊名：Experimental Eye Research
- 出版年：2015
- 出版时间：December 2015
- 年：2015
- 卷：141
- 期：Complete
- 页码：125-138
- 全文大小：1228 K
文摘
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The biomechanical environment within the eye is of interest in glaucoma, but is complex and difficult to determine.
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To understand this environment, researchers are using finite element modeling and measurements of tissue deformation and microstructure.
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Recent advances in these areas have provided better understanding of how tissue properties influence development and susceptibility of glaucoma.
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The potential of this body of work to translate into new diagnostic tools, IOP control strategies, and neural protection strategies is exciting.
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The article concludes with important open research questions.