Gold(I)-catalyzed sequential cycloisomerization/bis-addition of o

详细信息    查看全文

• 作者：C. Praveen ; Y. Wilson Sagayaraj ; P.T. Perumal
• 刊名：Tetrahedron Letters
• 出版年：2009
• 出版时间：11 February 2009
• 年：2009
• 卷：50
• 期：6
• 页码：644-647
• 全文大小：177 K

文摘

An efficient synthesis of bis(indolyl)methanes and di(indolyl)indolin-2-ones has been developed by a sequential approach involving gold(I)-catalyzed cycloisomerization/bis-addition of o-ethynylanilines with various aldehydes and isatins, respectively. This methodology opens clean and synthetically competitive alternative to the already established procedures of the synthesis of bis(indolyl)methanes and di(indolyl)indolin-2-ones.