Secular trends and predictors of mortality in acute lymphoblastic leukemia for children of low socioeconomic level in Northeast Brazil
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- 作者：Simone Santana Viana simonesvi@yahoo.com.br" class="auth_mail" title="E-mail the corresponding author ; Leyla Manoella Maurí ; cio Rodrigues de Lima ylla.lmmrl@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Juliana Brito do Nascimento julianabriton@hotmail.com" class="auth_mail" title="E-mail the corresponding author ; Carlos André ; Ferreira Cardoso cafcardoso@live.com" class="auth_mail" title="E-mail the corresponding author ; Ana Carolina Dantas Rosá ; rio caroldantasr@hotmail.com" class="auth_mail" title="E-mail the corresponding author ; Cristiano de Queiroz Mendonç ; a cristiano@iocm.com.br" class="auth_mail" title="E-mail the corresponding author ; Osvaldo Alves de Menezes-Neto oamneto28@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Rosana Cipolotti ; rosanaci@yahoo.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Acute lymphoblastic leukemia ; Mortality ; Infection ; Low socioeconomic level ; Children
- 刊名：Leukemia Research
- 出版年：2015
- 出版时间：October 2015
- 年：2015
- 卷：39
- 期：10
- 页码：1060-1065
- 全文大小：241 K
文摘
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We focused our study on the issues faced by clinicians treating children with ALL in the lower socioeconomic areas of Brazil.
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We evaluated the results of 35 years of LLA treatment comparing a historical cohort of 25 years to a more recent cohort of 10 years.
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Our study highlights that abandonment is not currently a major cause of treatment failure.
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We identified that infection during induction is the major component associated to mortality.