The pitfall of treating low bone turnover: Effects on cortical porosity
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- 作者：Maria Julia C.L.N. Araujoa ; Cristina Karohlb ; Rosilene M. Eliasa ; Fellype C. Barretoc ; f ; Daniela Veit Barretoc ; Maria Eugenia F. Canzianid ; Aluizio B. Carvalhod ; Vanda Jorgettia ; Rosa M.A. Moysesa ; e ; rosa.moyses@uol.com.br" class="auth_mail" title="E-mail the corresponding author
- 关键词：Cortical bone ; Bone biopsy ; Hemodialysis ; Parathyroid hormone ; Mineral metabolism
- 刊名：Bone
- 出版年：2016
- 出版时间：October 2016
- 年：2016
- 卷：91
- 期：Complete
- 页码：75-80
- 全文大小：891 K
文摘
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We analyzed cortical porosity (Ct.Po) in patients on hemodialysis enrolled in a previous randomized clinical trial.
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Ct.Po was already high at baseline in the majority of patients and correlated with PTH levels, despite turnover status.
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Ct.Po increased after one-year in most patients, and neither gender nor any choice of therapy has affected Ct.Po increase.
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The increase in Ct.Po was significant only in non-white patients and correlated with the delta of PTH.