A Common Platform for Antibiotic Dereplication and Adjuvant Discovery

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• 作者：Georgina Cox¹ ; Arthur Sieron¹ ; Andrew M. King¹ ; Gianfranco De Pascale¹ ; ² ; Andrew C. Pawlowski¹ ; Kalinka Koteva¹ ; Gerard D. Wright¹ ; ³ ; ^{wrightge@mcmaster.ca}
• 关键词：antibiotic ; dereplication ; potentiation ; antibiotic resistance ; natural products ; adjuvant
• 刊名：Cell Chemical Biology
• 出版年：2017
• 出版时间：19 January 2017
• 年：2017
• 卷：24
• 期：1
• 页码：98-109
• 全文大小：2347 K
• 卷排序：24

文摘

Development of a uniform antibiotic resistance platform (the ARP) The ARP is a versatile tool with dual functions The ARP allows for the discovery of new antibiotic adjuvants In dereplication mode, the ARP identifies common antibiotics