Antioxidant and anticancer effects and bioavailability studies of the flavonoid baicalin and its oxidovanadium(IV) complex

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• 作者：Juan J. Martí ; nez Medina^a ; ¹ ; Luciana G. Naso^b ; ¹ ; Ana L. Pé ; rez^c ; Alberto Rizzi^c ; Evelina G. Ferrer^b ; Patricia A.M. Williams^b ; ^{williams@quimica.unlp.edu.ar}
• 关键词：Oxidovanadium(IV) complex ; Baicalin ; Antioxidant ; Anticancer ; BSA binding
• 刊名：Journal of Inorganic Biochemistry
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：166
• 期：Complete
• 页码：150-161
• 全文大小：1429 K
• 卷排序：166

文摘

Oxidovanadium(IV) interacted with baicalin through the phenoxide anions. Consequent improvement of the antioxidant effects by coordination. Oxidative stress mechanism in the cancer cell-killing activity of the complex. Suppression of the anticancer effect by non-enzymatic antioxidants. Ligand and complex could be transported and stored by bovine serum albumin.