A new multiresponse optimization approach in combination with a D-Optimal experimental design for the determination of biogenic amines in fish by HPLC-FLD
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- 作者：A. Herreroa ; S. Sanllorentea ; C. Regueraa ; M.C. Ortiza ; mcortiz@ubu.es" class="auth_mail" title="E-mail the corresponding author ; L.A. Sarabiab
- 关键词：Multiresponse optimization ; D-optimal design ; Biogenic amines ; HPLC-FLD ; Derivatization ; Fish
- 刊名：Analytica Chimica Acta
- 出版年：2016
- 出版时间：16 November 2016
- 年：2016
- 卷：945
- 期：Complete
- 页码：31-38
- 全文大小：747 K
文摘
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New strategy simpler and more affordable than others for multiresponse optimization.
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10 experimental factors and 9 experimental responses are optimized with 23 runs.
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In conjunction to a D-optimal design it reduces economic, time and environmental cost.
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Successfully applied to determine eight biogenic amines in swordfish by HPLC-FLD.