Dynamic pulmonary hyperinflation occurs without expiratory flow limitation in chronic heart failure during exercise

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• 作者：Stefania Chiari ; Chiara Torregiani ; Enrico Boni ; Sonia Bassini ; Enrico Vizzardi ; Claudio Tantucci
• 关键词：Exercise ; Chronic heart failure ; Pulmonary hyperinflation ; Expiratory flow limitation ; Negative expiratory pressure ; Inspiratory capacity
• 刊名：Respiratory Physiology & Neurobiology
• 出版年：2013
• 出版时间：1 October, 2013
• 年：2013
• 卷：189
• 期：1
• 页码：34-41
• 全文大小：718 K

文摘

To assess the occurrence of tidal expiratory flow limitation (EFL) and/or dynamic pulmonary hyperinflation (DH) in chronic heart failure (CHF) during exercise 15 patients with stable systolic CHF, aged 69 ¡À 6 yr, underwent pulmonary function testing and incremental cardio-pulmonary exercise testing. They subsequently performed constant load exercise testing at 30, 60 and 90 % of respective maximum workload. At each step the presence of EFL, by negative expiratory pressure technique, and changes in inspiratory capacity (IC) were assessed. Ejection fraction amounted to 36 ¡À 6 % and , peak (77 ¡À 19 % pred.) was reduced. EFL was absent at any step during constant load exercise. In 6 patients IC decreased more than 10 % pred. at highest step. Only in these patients TLC, FRC, RV FEF_{25-75 %} and DL_CO were decreased at rest. , peak correlated with DL_CO, TLC and IC at rest and with IC (r² = 0.59; p < 0.001) and decrease in IC (r² = 0.44; p < 0.001) at 90 % of maximum workload. During exercise CHF patients do not exhibit EFL, but some of them develop DH that is associated with lower , peak.