A Meta-Analysis of Miniaturized Versus Conventional Extracorporeal Circulation in Valve Surgery

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• 作者：Chuangshi Wang ; MM^a ; Kun Hua ; PhD^b ; Lu Yin ; PhD^a ; Yang Wang ; MSc^a ; Wei Li ; PhD^a ; ^{liwei@mrbc-nccd.com" class="auth_mail" title="E-mail the corresponding author}
• 关键词：AVR ; aortic valve replacement ; CABG ; coronary artery bypass grafting ; CECC ; conventional extracorporeal circulation ; CI ; confidence interval ; CPB ; cardiopulmonary bypass ; ICU ; intensive care unit ; MECC ; miniaturized extracorporeal circulation ; RCT ; randomized controlled trial ; RR ; risk ratio ; WMD ; weighted mean difference
• 刊名：The Annals of Thoracic Surgery
• 出版年：2016
• 出版时间：December 2016
• 年：2016
• 卷：102
• 期：6
• 页码：2099-2108
• 全文大小：1340 K

文摘

The effects of miniaturized extracorporeal circulation in patients operated on for heart valve surgery are still inconsistent. We performed a meta-analysis of eight studies involving 1,011 patients to evaluate the comprehensive effects of miniaturized extracorporeal circulation. The results suggested its application significantly reduced the length of stay in the intensive care unit and total hospital stay after heart valve surgery, but no significant effects on reducing postoperative morbidity and mortality were observed. Further studies with long-term follow-up are needed to confirm our results.