Antidiarrhoeal efficacy of Mangifera indica seed kernel on Swiss albino mice

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• 作者：S Rajan ; H Suganya ; T Thirunalasundari ; S Jeeva
• 关键词：Antidiarrhoeal activity ; Gastroenteritis ; Diarrhoea ; Mangifera indica ; Seed kernel extracts
• 刊名：Asian Pacific Journal of Tropical Medicine
• 出版年：2012
• 出版时间：August, 2012
• 年：2012
• 卷：5
• 期：8
• 页码：630-633
• 全文大小：268 K

文摘

Objective

To examine the antidiarrhoeal activity of alcoholic and aqueous seed kernel extract of Mangifera indica (M. indica) on castor oil-induced diarrhoeal activity in Swiss albino mice.

Methods

Mango seed kernels were processed and extracted using alcohol and water. Antidiarrhoeal activity of the extracts were assessed using intestinal motility and faecal score methods.

Results

Aqueous and alcoholic extracts of M. indica significantly reduced intestinal motility and faecal score in Swiss albino mice.

Conclusions

The present study shows the traditional claim on the use of M. indica seed kernel for treating diarrhoea in Southern parts of India.