Fundamental amino acid mass distributions and entropy costs in proteomes
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- 作者：Jean Lehmanna ; Albert Libchaberb ; c ; Benjamin D. Greenbaumb ; d ; benjamin.greenbaum@mssm.edu" class="auth_mail" title="E-mail the corresponding author
- 关键词：Genome evolution ; Genetic code origin ; Amino acid statistics ; Extremophiles
- 刊名：Journal of Theoretical Biology
- 出版年：2016
- 出版时间：7 December 2016
- 年：2016
- 卷：410
- 期：Complete
- 页码：119-124
- 全文大小：522 K
文摘
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Amino acid mass and frequency are negatively correlated across all branches of life.
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Cysteine and leucine are outliers, as quantified by the entropic cost of deviation.
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Degeneracy partially enforces the mass-frequency relationship in the genetic code.
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Stability can drive the decay of mass-frequency correlations in extremophiles.