文摘
RTS,S has the potential to substantially reduce malaria burden in children in endemic Africa. Adding RTS,S to routine malaria control is potentially highly cost-effective. At PfPR2–10 > 10% predicted cost-effectiveness averages $136 per DALY averted. Under conservative assumptions predicted cost-effectiveness of RTS,S is, at most, doubled. Differences in country epidemiology and healthcare delivery result in substantial variation in predicted impact.