Low oxygen tension induces Krüppel-Like Factor 6 expression in trophoblast cells
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- 作者：A.C. Raccaa ; M.E. Ridanoa ; C.L. Bandeirab ; E. Bevilacquab ; E. Avvad Portaric ; S. Genti-Raimondia ; C.H. Grahamd ; 1 ; G.M. Panzetta-Dutaria ; 1 ; gpan@fcq.unc.edu.ar" class="auth_mail" title="E-mail the corresponding author
- 关键词：Hypoxia ; Krü ; ppel-Like Factor 6 ; Hypoxia inducible factor-1α ; Placenta ; Trophoblast
- 刊名：Placenta
- 出版年：2016
- 出版时间：September 2016
- 年：2016
- 卷：45
- 期：Complete
- 页码：50-57
- 全文大小：3443 K
文摘
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Transcription factor KLF6 is expressed in villous and extravillous trophoblasts.
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Low oxygen tension early and transiently increases KLF6 levels.
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HIF-1α is involved in the hypoxia-mediated induction of KLF6 expression.