Talarolutins A-D: Meroterpenoids from an endophytic fungal isolate of Talaromyces minioluteus
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- 作者：Amninder Kaura ; Huzefa A. Rajaa ; Dale C. Swensonb ; Rajesh Agarwalc ; Gagan Deepc ; Joseph O. Falkinham IIId ; Nicholas H. Oberliesa ; nicholas_oberlies@uncg.edu" class="auth_mail" title="E-mail the corresponding author
- 关键词：Meroterpenoid ; Fungal endophyte ; Talaromyces minioluteus ; Milk thistle ; Silybum marianum ; Asteraceae
- 刊名：Phytochemistry
- 出版年：2016
- 出版时间：June 2016
- 年：2016
- 卷：126
- 期：Complete
- 页码：4-10
- 全文大小：556 K
文摘
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An endophytic fungus from surface-sterilized leaves of Silybum marianum (milk thistle) was investigated.
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A total of five compounds was isolated from the fungal endophyte, Talaromyces minioluteus.
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Among them, four were identified as meroterpenoids (named talarolutins A–D).
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These meroterpenoids are of mixed biosynthetic origin, likely derived from terpene and polyketide subunits.
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X-ray crystallography, NMR, and MS techniques were utilized for determining the structures of the compounds.