Interleukin-6 gene polymorphisms correlate with the progression of nephropathy in Chinese patients with type 2 diabetes: A prospective cohort study
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- 作者：Wen-Tsan Changa ; b ; Meng-Chuan Huangc ; d ; Hsin-Fang Chunge ; Yen-Feng Chiuf ; Pao-Shan Chenc ; Fang-Pei Chenc ; Chun-Yi Leef ; Shyi-Jang Shing ; Shang-Jyh Hwangh ; Ya-Fang Huangf ; Chih-Cheng Hsuf ; i ; j ; cch@nhri.org.tw" class="auth_mail" title="E-mail the corresponding author
- 关键词：Interleukin-6 ; Polymorphisms ; Type 2 diabetes ; Diabetic nephropathy ; Prospective study
- 刊名：Diabetes Research and Clinical Practice
- 出版年：2016
- 出版时间：October 2016
- 年：2016
- 卷：120
- 期：Complete
- 页码：15-23
- 全文大小：750 K
文摘
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Interleukin-6 (IL-6) serves a candidate gene involved in susceptibility to nephropathy.
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This longitudinal study focused on 568 type 2 diabetes patients with normoalbuminuria.
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Development of diabetic nephropathy over 5.3 years was examined.
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IL-6 polymorphisms is associated with progression of nephropathy in diabetic patients.