Neuroprotection during aortic surgery

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• 作者：Helen Lindsay ; FANZCA ^{Helenl@adhb.govt.nz" class="auth_mail" title="E-mail the corresponding author} (Clinical Fellow) ; Coimbatore Srinivas ; MD ; FRCA ; FRCPC ^{Coimbatore.Srinivas@uhn.ca" class="auth_mail" title="E-mail the corresponding author} (Consultant Anesthetist) ; George Djaiani ; MD ; DEAA ; FRCA ; FRCPC ; ^{George.djaiani@uhn.on.ca" class="auth_mail" title="E-mail the corresponding author} (Consultant Anesthetist)
• 关键词：neuroprotection ; aortic surgery ; risk factors ; neurologic injury ; spinal cord injury ; stroke ; temporary neurological dysfunction ; neuromonitoring
• 刊名：Best Practice Research Clinical Anaesthesiology
• 出版年：2016
• 出版时间：September 2016
• 年：2016
• 卷：30
• 期：3
• 页码：283-303
• 全文大小：944 K

文摘

Neurological injury is a major limitation of aortic surgery, whether it involves spinal cord injury following intervention to the thoracoabdominal aorta, or stroke following surgery on the arch and ascending aorta. Despite an extensive body of literature and various proposals, a completely effective strategy to prevent or treat neurological injury remains elusive. In this article, we summarise the evidence for established and emerging strategies, and review current concepts in pathophysiology and risk assessment as they relate to neurological injury.