• 作者：A. Ortega Eslava^a ; ^{aortega@unav.es} ; F. Puigventó ; s Latorre^b ; B. Santos-Ramos^c ; B. Calderon Hernanz^d ; M. Vilanova Boltó ; ^d ; en representació ; n del Grupo de Evaluació ; n de Novedades ; Estandarizació ; n e Investigació ; n en Selecció ; n de Medicamentos (GENESIS) de la Sociedad Espa&ntilde ; ola de Farmacia Hospitalaria (SEFH)
• 关键词：Evaluació ; n de medicamentos ; Formularios ; Hospital ; Listas-guí ; a ; Evaluació ; n de tecnologí ; as ; Decisió ; n ; Comisió ; n de Farmacia y Terap&eacute ; utica ; Internet ; Farmac&eacute ; uticos ; Espa&ntilde ; a
• 刊名：Farmacia Hospitalaria
• 出版年：2011
• 出版时间：May-June 2011
• 年：2011
• 卷：35
• 期：3
• 页码：140-147
• 全文大小：162 K

Objective

To analyse the assessment reports published on the GENESIS webpage (Group for Innovation, Assessment, Standardisation and Research in the Selection of Drugs) and assess the variability of the group's proposals to include drugs in the Formulary.

Method

We analysed reports published by hospitals on the GENESIS webpage between 2004 and 2007. Data were collected on drugs and indications, ATC group, open or restricted access publications, hospital, and publication date. We drafted a questionnaire that would measure to what extent to what extent the 9-section model recomended by GENESIS was included in each report. For drugs with two or more reports, we analysed whether the recommendation coincided and the possible cause in the event of conflict.

Results

We analysed 416 reports corresponding to 185 different drug indications. 93 % included 6 or more of the recommended sections, a number which increased over time. The most frequently included sections were: approved indications (92 % ), mechanism of action (95 % ), and references (86 % ) (percentages from 2007). Sections which had an increasing but lower percentage were: differential characteristics (60 % ), literature search method (40 % ) and conclusions with a summary of efficacy, safety and cost data (52 % ). 73 % of which had definite recommendations, which coincided for 42 out of the 67 drugs with more than one recommendation report.

Conclusions

The work carried out by the GENESIS group has enabled Spanish hospitals to share their drug assessment reports and making them more complete, although there are still some aspects that can be improved.