刊名:International Journal of Biological Macromolecules
出版年:2017
出版时间:January 2017
年:2017
卷:94
期:part_PA
页码:386-395
全文大小:1436 K
卷排序:94
文摘
The review details folding and misfolding of protein and its clinical implications. Neurodegenerative diseases are also and outcome of protein misfolding and aggregation. Interaction of nanoparticles with proteins alters the protein conformation and prevents protein aggregation. Currently nanoparticles are employed as artificial chaperones and for detection of protein-folding intermediates. Nanoparticles can be used in developing targeted novel treatment for fatal diseases.