Abdominal adiposity with respect to the proportion of intra-abdominal visceral fat to extra-abdominal fat (V/S ratio) in Japanese childhood obesity

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• 作者：Jin Yamaguchi ; Tatsuya Oguni ; Kazutaka Konishi ; Makoto Mino
• 刊名：Pathophysiology
• 出版年：1996
• 出版时间：March 1996
• 年：1996
• 卷：3
• 期：1
• 页码：29-35
• 全文大小：513 K

文摘

The aim of this study was to assess the influence of intra-abdominal fat accumulation in obese children upon lipids, glucose metabolism, and blood pressure. Intra-abdominal fat accumulation was quantified by the intra-abdominal visceral fat to extra-abdominal fat ratio (V/S ratio) using CT scanning. The subjects were simple obese boys (35) and girls (24) aged 10.6 ± 2.1 years. The following parameters were calculated: V/S ratio from CT analysis at umbilical level, percentage of ideal body weight ( % IBW), body mass index (BMI), and waist-to-hip ratio (WHR) from anthropometric measurements. Replies to questionnaires concerning duration of obesity and history of family obesity were obtained. Blood pressure and biochemical parameters including transaminases, serum lipids, blood glucose and insulin were measured. Visceral fat obesity was present in 15.7 % of all the subjects. Visceral fat syndrome was seen in some cases. The V/S ratio displayed a weak positive correlation with GOT (r = 0.352, P = 0.0078) and GPT (r = 0.351, P = 0.0075), but no correlation with serum lipids, blood glucose, insulin, or blood pressure. Stepwise and multiple regression analysis revealed that GOT and GPT depended upon the V/S ratio, age, and duration of obesity.

It was concluded that intra-abdominal fat accumulation in childhood can cause fatty liver when combined with aging and persistent obesity, and that obese children with fatty liver are likely to develop visceral fat syndrome in the future.