Effect of multipurpose solutions on in vivo surface wettability of a silicone hydrogel lens

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• 作者：Jason Ki-kit Lau ; BSc. (Hons) Optom. ; ^{kklau@polyu.edu.hk" class="auth_mail" title="E-mail the corresponding author} ; Hoi-Ting So ; BSc. (Hons) Optom. ; Tsz-Kit Chiang ; BSc. (Hons) Optom. ; Pauline Cho ; Ph.D. FAAO FBCLA
• 关键词：Wettability ; PL-NITBUT ; Multipurpose solution ; Silicone hydrogel
• 刊名：Contact Lens and Anterior Eye
• 出版年：2016
• 出版时间：December 2016
• 年：2016
• 卷：39
• 期：6
• 页码：461-465
• 全文大小：745 K

文摘

To compare the in vivo surface wettability of silicone hydrogel (SiHy) contact lenses pre-soaked overnight in different multipurpose solutions (MPS) and normal saline.

Methods

In this double-blinded, randomized and self-controlled study, 36 subjects were fitted with three pairs of contact lenses (senofilcon A) pre-soaked overnight in five different MPS and saline in a randomized order. Each pair of lenses (pre-soaked in two different solutions the night before) were worn for 15 min before assessment of pre-lens non-invasive tear break-up time (PL-NITBUT) using the Medmont corneal topographer (video recording). Corneal integrity was assessed using a slit lamp and a resting interval of 20 min was allowed between each pair of lenses to ensure post-lens wear corneal integrity.

Results

Thirty subjects completed the study. The median PL-NITBUT ranged from 2.84 s to 3.08 s with lenses pre-soaked in different MPS, compared to 2.78 s with lenses pre-soaked in saline. No significant differences in PL-NITBUT were found among lenses pre-soaked in different solutions (p = 0.647).

Conclusion

In vivo surface wettability, in terms of PL-NITBUT after 15 min of lens wear, of senofilcon A contact lenses pre-soaked overnight in different MPS were not significantly different from those pre-soaked in saline.