Successfully expressed and purified the mammalian rhIGFBP7, an IGF-1 targeted inhibition protein, using transient gene expression and conventional non-affinity column chromatography purification method.
High quality material IGFBP7 was generated for further pre-clinical drug development studies.
Transient gene expression technology through optimization of vectors is practical to be used for production of recombinant non-antibody protein products for biopharmaceutical development.