IGFBP7 is involved in abalone metamorphosis
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- 作者：Guodong Wanga ; Na Lia ; Lili Zhanga ; Longhui Zhanga ; Ziping Zhangb ; Yilei Wanga ; ylwang@jmu.edu.cn" class="auth_mail" title="E-mail the corresponding author
- 关键词：BC ; blank control ; Dilp ; Drosophila insulin-like peptide ; dsRNA ; double-stranded RNA ; FSW ; filtered seawater ; GABA ; γ-aminobutyric acid ; GFP ; green fluorescent protein ; hpf ; hours post-fertilization ; IB ; insulin-like growth factors binding ; IIS ; insulin/insulin-like growth factor signaling pathway ; IGFBP7 ; insulin-like growth factor binding protein 7 ; IGFBPs ; insulin-like growth factor binding proteins ; IGFR ; insulin-like growth factor receptor ; ILPs ; insulin-like peptides ; Imp-L2 ; imaginal morp
- 刊名：Aquaculture
- 出版年：2016
- 出版时间：20 January 2016
- 年：2016
- 卷：451
- 期：Complete
- 页码：377-384
- 全文大小：1041 K
文摘
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saIGFBP7 has a high expression level in metamorphosis of Haliotis diversicolor
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saIGFBP7 transcripts were mainly localized in the foot of competent larva.
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dsRNA exposure of saIGFBP7 decreased metamorphosis, but insulin had no effect.
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PI3K, ERKα, AKT and saIGFBP7 reduced in dsRNA exposure, AKT rose in insulin inducing.