Reference intervals of urinary acute kidney injury (AKI) markers [IGFBP7]∙[TIMP2] in apparently healthy subjects and chronic comorbid subjects without AKI
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- 作者：Nandkishor S. Chindarkara ; Lakhmir S. Chawlab ; Joely A. Straseskic ; Saeed A. Jortanid ; Denise Uettwiller-Geigere ; Robert R. Orrf ; John A. Kellumg ; Robert L. Fitzgeralda ; rfitzgerald@ucsd.edu" class="auth_mail" title="E-mail the corresponding author
- 关键词：AKI ; acute kidney injury ; IGFBP7 ; insulin-like growth factor-binding protein 7 ; KDIGO ; kidney disease improving global outcomes ; NGAL ; neutrophil gelatinase-associated lipocalin ; TIMP-2 ; tissue inhibitor of metalloproteinases-2
- 刊名：Clinica Chimica Acta
- 出版年：2016
- 出版时间：15 January 2016
- 年：2016
- 卷：452
- 期：Complete
- 页码：32-37
- 全文大小：550 K
文摘
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Reference ranges for the AKI risk biomarkers IGFBP7 and TIMP-2 are described.
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We demonstrate that these markers are not elevated in chronic stable comorbid conditions.
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The overall reference interval for [IGFBP7]∙[TIMP-2] in urine is 0.04–2.22 (ng/mL)2.