Acquisition and inhibition of conditioned fear is modulated by individual stimulus fear-relevance

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• 作者：Jö ; rg Neubert^a ; ^{joerg.neubert@uni-greifswald.de} ; Katja Hillbrandt^a ; Mathias Weymar^a ; ^b ; Alfons O. Hamm^a ; Julia Wendt^a
• 关键词：Fear learning ; Safety learning ; Conditioned inhibition ; Spiders ; Phobia ; Startle blink response
• 刊名：Neurobiology of Learning and Memory
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：137
• 期：Complete
• 页码：114-122
• 全文大小：924 K
• 卷排序：137

文摘

The startle response is modulated by stimulus fear relevance in the AX+/BX− paradigm. Individual fear and stimulus fear-relevance modulate fear acquisition and inhibition. Fear relevant stimuli can become safety signals for subjects with elevated fear. The Rescorla-Wagner-Model correctly predicts fear acquisition and inhibition.