Quantitative Positron Emission Tomography (QPET) could be used as a biomarker.
Clinical trial qualification (CTQ) of PET scanners is mandatory for reliable use of QPET.
Variability in activity measurements at 95% CI was 74.0% (18F) and 20.5% (68Ge).
100% (with 68Ge) and 28% (with 18F) of PET scanners passed CTQ at first round.
CTQ with 68Ge vs 18F filled phantom assure lower variability and eases the process.