Clinical relevance of colorectal cancer molecular subtypes

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• 作者：Nuria Rodriguez-Salas^a ; ^{nuria.rodriguez@salud.madrid.org} ; Gema Dominguez^b ; Rodrigo Barderas^c ; Marta Mendiola^d ; Xabier Garcí ; a-Albé ; niz^e ; Juan Maurel^f ; Jaime Feliu Batlle^a ; ^g
• 关键词：Colorectal cancer ; Molecular subtypes ; Personalized treatment
• 刊名：Critical Reviews in Oncology/Hematology
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：109
• 期：Complete
• 页码：9-19
• 全文大小：1006 K
• 卷排序：109

文摘

The comprehensive study of molecular changes in colorectal cancer identifies potential therapeutic targets. The integrative analysis of distinct molecular sybtypes can led to individualized approach to therapeutics. The predictive and prognostic approach is useful in adjuvant setting and also in treatment selection in metastasic disease in CRC patients.