Discovering the enzyme mimetic activity of metal-organic framework (MOF) for label-free and colorimetric sensing of biomolecules
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- 作者：Ying Wang ; Yingjing Zhu ; Atsebeha Binyam ; Misha Liu ; Yinan Wu ; Fengting Li ; fengting@tongji.edu.cn" class="auth_mail" title="E-mail the corresponding author
- 关键词：MOF ; Enzyme mimetic ; Label-free ; Colorimetric ; Biosensing
- 刊名：Biosensors and Bioelectronics
- 出版年：2016
- 出版时间：15 December 2016
- 年：2016
- 卷：86
- 期：Complete
- 页码：432-438
- 全文大小：1690 K
文摘
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Enzyme mimetic activity of Fe-MIL-88A has been utilized successfully for colorimetric sensing of biomolecules.
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The introduction of aptamer as the molecular recognition element can greatly expand the detection scope from H2O2 to complicated biomolecules.
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This sensing system displays remarkable properties including label-free, simplicity, short assay time, sensitive colorimetric detection with nicked eyes and high specificity.