Cloning and the mRNA expression of a C-type lectin with one carbohydrate recognition domain from Fenneropenaeus merguiensis in response to pathogenic inoculation
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- 作者：Phanthipha Runsaeng ; Supattra Thepnarong ; Onnicha Rattanaporn ; Prapaporn Utarabhand ; prapaporn.u@psu.ac.th" class="auth_mail" title="E-mail the corresponding author
- 关键词：Fenneropenaeus merguiensis ; QPD motif ; RNAi ; Single-CRD lectin ; Vibrio harveyi ; WSSV
- 刊名：Molecular and Cellular Probes
- 出版年：2015
- 出版时间：December 2015
- 年：2015
- 卷：29
- 期：6
- 页码：365-375
- 全文大小：2640 K
文摘
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A novel C-type lectin was cloned from the stomach of Fenneropenaeus merguiensis.
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Its mRNA expression was detected specifically in the stomach.
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After challenge with V. harveyi or WSSV, the FmLC2 expression was up-regulated.
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RNAi silencing resulted in dramatically reduction of the lectin expression.
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This new lectin may serve as the receptor molecules for invading pathogens.