Effect of IL28B genotype on hepatitis B and C virus infection
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- 作者：Albert Friedrich Stä ; ttermayer ; Peter Ferenci peter.ferenci@meduniwien.ac.at" class="auth_mail" title="E-mail the corresponding author
- 刊名：Current Opinion in Virology
- 出版年：2015
- 出版时间：October 2015
- 年：2015
- 卷：14
- 期：Complete
- 页码：50-55
- 全文大小：310 K
文摘
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IL28B polymorphism is strongly associated with IFN-induced viral clearance in chronic HCV infection.
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IL28B polymorphism is strongly associated with spontaneous viral clearance in acute HCV infection.
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By contrast, IL28B polymorphism has only limited impact in all-oral antiviral treatment against HCV.
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The influence of IL28B polymorphism in HBV infection is controversial.