Research findings from nonpharmaceutical intervention studies for pandemic influenza and current gaps in the research

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• 作者：Allison E. Aiello ; Rebecca M. Coulborn ; Tomas J. Aragon ; Michael G. Baker ; Barri B. Burrus ; Benjamin J. Cowling ; Alasdair Duncan ; Wayne Enanoria ; M. Patricia Fabian ; Yu-hui Ferng ; Elaine L. Larson ; Ga
• 关键词：Hand hygiene ; masks ; transmission ; infection control
• 刊名：American Journal of Infection Control
• 出版年：2010
• 出版时间：May 2010
• 年：2010
• 卷：38
• 期：4
• 页码：251-258
• 全文大小：159 K

文摘

In June 2006, the Centers for Disease Control and Prevention released a request for applications to identify, improve, and evaluate the effectiveness of nonpharmaceutical interventions (NPIs)—strategies other than vaccines and antiviral medications—to mitigate the spread of pandemic influenza within communities and across international borders (RFA-CI06-010). These studies have provided major contributions to seasonal and pandemic influenza knowledge. Nonetheless, key concerns were identified related to the acceptability and protective efficacy of NPIs. Large-scale intervention studies conducted over multiple influenza epidemics, as well as smaller studies in controlled laboratory settings, are needed to address the gaps in the research on transmission and mitigation of influenza in the community setting. The current novel influenza A (H1N1) pandemic underscores the importance of influenza research.