Cytostatic drugs in environmental samples: An update on the extraction and determination procedures
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- 作者：S. Santana-Viera ; S. Montesdeoca-Esponda ; Z. Sosa-Ferrera ; J.J. Santana-Rodrí ; guez ; josejuan.santana@ulpgc.es" class="auth_mail" title="E-mail the corresponding author
- 关键词：Cytostatic agents ; Emerging contaminants ; Environmental samples ; Liquid chromatography ; Gas chromatography
- 刊名：TrAC Trends in Analytical Chemistry
- 出版年：2016
- 出版时间：June 2016
- 年：2016
- 卷：80
- 期：Complete
- 页码：373-386
- 全文大小：845 K
文摘
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The methods for the analysis of cytostatic drugs in environmental samples are overviewed.
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LC–MS (liquid chromatography–mass spectrometry) is the most used determination technique.
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Cytostatic compounds are measured in µg L−1 in hospital effluents and in ng g−1 in sludges.
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Metabolites can be found in higher concentrations than parent compounds.