Direct voltammetric detection of ceruloplasmin in blood in presence of other paramagnetic species
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- 作者：Edyta MatysiakaAuthor Vitae ; Barbara WagnerbAuthor Vitae ; Michał BystrzejewskiaAuthor Vitae ; Ireneusz P. GrudzinskicAuthor Vitae ; Anna M. Nowickaa ; anowicka@chem.uw.edu.pl" class="auth_mail" title="E-mail the corresponding authorAuthor Vitae
- 关键词：Ceruloplasmin ; Electrochemistry ; Direct determination ; Core&ndash ; shell type ferromagnetic nanoparticles ; Rat blood ; Paramagnetic components of blood
- 刊名：Sensors & Actuators: B. Chemical
- 出版年：2015
- 出版时间：31 December 2015
- 年：2015
- 卷：221
- 期：Complete
- 页码：1461-1468
- 全文大小：1390 K
文摘
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The presence of Fe@C Nps layer at electrode surface and the presence of magnetic field guarantee the electroactivity of ceruloplasmin.
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The ferromagnetic electrode modifier (Fe@C Nps) and external magnetic field allow the determination of Cp without any pre-concentration step.
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Direct voltammetric sensor for detection of ceruloplasmin in blood has been developed.
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The proposed Cp sensor is sensitive, reproducible and has very low limit of detection (pM level).