Association of Ideal Cardiovascular Health and Brachial-Ankle Pulse Wave Velocity: A Cross-Sectional Study in Northern China

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• 作者：Na Yan ; MD^* ; Yong Zhou^&dagger ; ; Youxin Wang ; PhD^* ; Anxin Wang ; MD^&dagger ; ; Xin Yang ; MD^* ; Alyce Russell ; MSc^&Dagger ; ; Shouling Wu ; MD ; PhD^§ ; ; ^{drwusl@163.com" class="auth_mail" title="E-mail the corresponding author} ; Xingquan Zhao ; MD^&dagger ; ; ^{zxq@vip.163.com" class="auth_mail" title="E-mail the corresponding author} ; Wei Wang ; MD ; PhD ; FFPH^* ; ^&Dagger ; ; ^{wei.wang@ecu.edu.au" class="auth_mail" title="E-mail the corresponding author}
• 关键词：Ideal cardiovascular health ; brachial&ndash ; ankle pulse wave velocity ; arterial stiffness ; epidemiology
• 刊名：Journal of Stroke and Cerebrovascular Diseases
• 出版年：2016
• 出版时间：January 2016
• 年：2016
• 卷：25
• 期：1
• 页码：41-48
• 全文大小：331 K

文摘

Brachial–ankle pulse wave velocity (baPWV) is an index for evaluating arterial stiffness and is recognized as an independent predictor of an impending cardiovascular event. Limited large-scale population data are available regarding the relationship between baPWV and the change in ideal cardiovascular health (CVH) status, particularly among Asians.

Methods

A random sample of 5199 participants (≥40 years of age; 40% women) was enrolled in a cross-sectional study in China to examine the association between ideal CVH and baPWV. Arterial stiffness was defined as a baPWV of 1400 cm/second or higher. Information on CVH was collected based on the American Heart Association's CVH definition by measuring all 7 components (nonsmoking status, body mass index, physical activity, healthy diet, normal total cholesterol, blood pressure, and fasting blood glucose), with 1 or 0 for each component, and a score from 0 to 7 for each participant.

Results

A significant and inverse association was found between the ideal CVH score and baPWV (P < .001). The adjusted odds ratios for arterial stiffness prevalence were .17 (95% confidence interval [CI], .11-.26), .26 (95% CI, .19-.35), .42 (95% CI, .32-.52), .54 (95% CI, .42-.69), and .69 (95% CI, .54-.89) for those with CVH scores of 7-6, 5, 4, 3, and 2, respectively, compared with those with a CVH score of 1-0 (P < .001). Similarly graded relationships were observed in different age and gender subgroups (P < .001).

Conclusion

The favorable score of ideal CVH was inversely related to baPWV in Chinese adults, supporting the use of ideal CVH metrics as a useful tool for public health efforts.