Expressed miRNAs target feather related mRNAs involved in cell signaling, cell adhesion and structure during chicken epidermal development
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- 作者：Weier Bao ; bao2@email.sc.edu" class="auth_mail" title="E-mail the corresponding author ; Matthew J. Greenwold greenwold@biol.sc.edu" class="auth_mail" title="E-mail the corresponding author ; Roger H. Sawyer rhsawyer@mailbox.sc.edu" class="auth_mail" title="E-mail the corresponding author
- 关键词：MicroRNA ; Chicken ; Feather ; Scale ; Evolution ; Genome ; β-Keratin ; Tenascin C ; ALDH1A3 and FGF20
- 刊名：Gene
- 出版年：2016
- 出版时间：15 October 2016
- 年：2016
- 卷：591
- 期：2
- 页码：393-402
- 全文大小：2026 K
文摘
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MicroRNAs are differentially expressed during avian epidermal development.
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Post-transcriptional modification (miRNAs) of β-keratins provides a mechanism for understanding the differences between mRNA expression data and the protein analysis data.
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The miRNA targeting of three major functional categories (cell signaling, cell adhesion and structural genes) of feather development genes indicates that miRNAs have had a diverse and important role in the evolution of feathers.