The role of bone sialoprotein in the tendon-bone insertion
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- 作者：Ryan Marinovicha ; &dagger ; ; Yohannes Soenjayab ; &dagger ; ; Gregory Q. Wallacec ; Andre Zuskovd ; Andrew Dunkmand ; Brian L. Fostere ; &Dagger ; ; Min Aof ; Kevin Bartmana ; Vida Lamg ; Amin Rizkallab ; g ; Frank Beierh ; Martha J. Somermanf ; David W. Holdsworthi ; Louis J. Soslowskyd ; Franç ; ois Lagugné ; -Labarthetc ; Harvey A. Goldberga ; g ; hagoldbe@uwo.ca" class="auth_mail" title="E-mail the corresponding author
- 关键词：Bone sialoprotein ; Osteopontin ; Enthesis ; Quadriceps tendon ; Supraspinatus tendon ; Calcified fibrocartilage
- 刊名：Matrix Biology
- 出版年：2016
- 出版时间：May-July 2016
- 年：2016
- 卷：52-54
- 期：Complete
- 页码：325-338
- 全文大小：2244 K
文摘
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We identified bone sialoprotein and osteopontin in the mineralized murine fibrocartilaginous entheses
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The quadricep tendon entheses in Bsp-/- mice are 28% longer than wild type mice at age 15 weeks
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Mechanical testing of the Bsp−/− patellar tendon revealed a thicker yet mechanically inferior tendon.
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Mineral content of the Bsp−/− enthesis, as measured by micro-CT and Raman spectroscopy, is normal.