Towards the biotechnological isomerization of branched sugars: d-tagatose-3-epimerase equilibrates both enantiomers of 4-C-methyl-ribulose with both enantiomers of 4-C-methyl-xylulose

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• 作者：Devendar Rao ; Akihide Yoshihara ; Pushpakiran Gullapalli ; Kenji Morimoto ; Goro Takata ; Filipa P. da Cruz ; Sarah F. Jenkinson ; Mark R. Wormald ; Raymond A. Dwek ; George W.J. Fleet ; Ken Izumori
• 关键词：Thermoelectric ; Power generation ; Self-powered ; Combustion ; Heating system
• 刊名：Tetrahedron Letters
• 出版年：2008
• 出版时间：12 May 2008
• 年：2008
• 卷：49
• 期：20
• 页码：3316-3321
• 全文大小：238 K

文摘

Microbial oxidation of 2-C-methyl-d-ribitol and 2-C-methyl-d-arabinitol by Gluconobacter thailandicus NBRC 3254 produces 4-C-methyl-l-ribulose and 4-C-methyl-d-ribulose, respectively. Further, 4-C-methyl-l-ribulose and 4-C-methyl-d-ribulose were equilibrated by d-tagatose-3-epimerase (DTE) with 4-C-methyl-l-xylulose and 4-C-methyl-d-xylulose, respectively. These transformations demonstrate that polyol dehydrogenase and DTE act on branched synthetic sugars. The green preparation of all of the stereoisomers of 4-C-methyl pentuloses illustrates the ability of biotechnology to generate novel branched monosaccharides.